Crohn’s disease causes thousands of people discomfort and decreases quality of life with symptoms such as stomach pain, diarrhea, fatigue and increased weight loss due to any foods needing to be avoided. Up until now doctors have been mystified as to why people develop Crohn’s.
A new study, however, may have cracked the reason why the inflammatory bowel condition flairs up in certain people and it could be down to a particular fungus and two types of bacteria that go towards developing the condition.
More than 100, 500 people in the BRITISH are stricken by the particular condition, which causes the chronic inflammation of the particular intestine.
Professor John Hermon-Taylor of St George’s Medical Center, London, has developed the vaccine that ought in order to be ready within the particular next five years.
This has already been examined successfully on animals plus second-stage trials are in order to start soon, with human being trials within the following three years.
Professor Hermon-Taylor is convinced that the bug – known because MAP (Mycobacterium avian paratuberculosis), found in animals plus passed into the meals chain – is the particular cause of most human being cases of Crohn’s illness.
When he tested patients with Crohn’s disease for MAP, he found the same bacteria in their intestines as in animals.
However, the Government’s Advisory Committee on the Microbiological Safety of Food insists that transmission to humans of MAP from animals is not proven, despite evidence of it getting into the milk supply.
The vaccine would be used to help cure existing sufferers of the illness by stimulating the body’s immune system to clear MAP from their bodies.
Three-quarters of people with Crohn’s disease require surgery to repair their damaged bowel, and half of those will need a second operation in ten years.
‘Around 80 per cent of people I have tested for Crohn’s have tested positive for MAP. We believe that the other 20 per cent have a genetic susceptibility to the disease,’ says the Professor.
Earlier this year, the Ministry of Agriculture Fisheries And Foods revealed that a national survey of milk had found the bug in 3 per cent of the milk supply.
But it still insists that there is no conclusive link between animal MAP and MAP found in humans. However, companies are heating milk for longer in an attempt to kill the bug. But even this might not be sufficient to give protection, warns Professor Hermon-Taylor.