Sherrill Franklin was clearing brush from around her Pennsylvania home the first time she was infected with Lyme disease. She never saw the miscreant tick, but it wasn’t long before she noticed a bulls-eye shaped rash, now known to be something of a hallmark of the disease. At the time, though, even her doctor was flummoxed. “This was the 1980s, and at that time nobody I knew had ever heard of Lyme disease,” Franklin says. “I went to the doctor and he said, ‘Wow, that sure is ugly… but I have no idea what it is!'” A brutal sore throat accompanied the rash, so she left with 5 days’ worth of an antibiotic for that irritation, which eventually went away. (Looking to take back control of your health? Prevention magazine has smart answers—get 2 FREE gifts when you subscribe today.)What lingered was an exhaustion so profound she had to abandon her shopping cart in the middle of the grocery store and a foggy mind that made it impossible to follow along when watching a movie. She knew something was wrong, but having recently become pregnant, she thought her symptoms were related instead to the pregnancy.